Perturb-Seq screen of 3200 DHS implicated in cell proliferation in K562 cells
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This is a sublibrary of the one designed for the proliferation screen, restricted to hit gRNAs (in distal DHSs, showing an effect on cell proliferation) in ~3,200 DHSs. Cells were transfected at a high MOI, with a median of 7 gRNAs per cell. The readout is single-cell RNA-seq, and includes data for both gRNAs protospacers and mRNA transcripts.
Cell Lines: K562
Assembly: hg38
DCPEXPR0000000040