Experiment Index
Filter Experiments
Assays
Experiment Source Type
Cell Line
Tissue Type
Functional Characterization Modality
Genome Assembly
Combine Experiments

Drag experiments here to select

Please select at least one experiment.
scCERES screen of 3200 DHS implicated in cell proliferation in K562 cells
＋
This is a sublibrary of the one designed for wgCERES, restricted to hit gRNAs (in distal DHSs, showing an effect on cell proliferation) in ~3,200 DHSs. Cells were transfected at a high MOI, with a median of 7 gRNAs per cell. The readout is single-cell RNA-seq, and includes data for both gRNAs protospacers and mRNA transcripts.
Cell Lines: k562
DCPEXPR0000000002
wgCERES proliferation screen of 112,025 DHSs in K562 cells
＋
Whole genome CRISPR-dCas9-based Epigenomic Regulatory Eelement Screening is an experiment aimed to measure the impact of the KRAB effector (CRISPRi) in cell proliferetion. This assay tested around 10 guide RNAs (gRNAs) in all >100,000 DNase-seq Hypersensitive Sites (DHSs) identified in K562.
Cell Lines: k562
DCPEXPR0000000003
scCERES screen of the MHC locus in WTC-11 induced pluripotent cells
＋
Briefly, a 3.5Mb region known as the MHC control locus was investigated, not only targeting open chromatin regions, but also GWAS hits for variants showing association with neuronal differentiation (please check this is correct with Lexi Bounds)
Cell Lines: iPSC
DCPEXPR0000000004
scCERES screen of the MHC locus in K562 cells
＋
Briefly, a 3.5Mb region known as the MHC control locus was investigated, not only targeting open chromatin regions, but also GWAS hits for variants showing association with neuronal differentiation
Cell Lines: k562
DCPEXPR0000000005
scCERES screen of the MHC locus in neural progenitor cells
＋
Briefly, a 3.5Mb region known as the MHC control locus was investigated, not only targeting open chromatin regions, but also GWAS hits for variants showing association with neuronal differentiation
Cell Lines: NPC
DCPEXPR0000000006
ATAC-STARR-seq screen of Chromatin Accessable Regions in k562 cells
＋
Cell Lines: k562
DCPEXPR0000000007
scCRISPRa screen of TFs in CD8+ T cells
＋
SaCas9 CRISPRa screens trying to identify which transcription factors (TFs) are responsible for making and maintaining a subset of CD8+ T cells. The same library targeting TF promoters is used with KRAB (CRISPRi) and p300 (CRISRPRa)
Cell Lines: CD8
DCPEXPR0000000008
scCRISPRi screen of TFs in CD8+ T cells
＋
SaCas9 CRISPRi screens trying to identify which transcription factors (TFs) are responsible for making and maintaining a subset of CD8+ T cells. The same library targeting TF promoters is used with KRAB (CRISPRi) and p300 (CRISRPRa)
Cell Lines: CD8
DCPEXPR0000000009
CRISPRi Flow-FISH CRISPR screen in K562 for PRDX2 (ENCSR006WCB)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000000A
CRISPRi Flow-FISH CRISPR screen in K562 for H1FX (ENCSR019BVO)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000000B
CRISPRi Flow-FISH CRISPR screen in K562 for PIM2 (ENCSR020TLT)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000000C
CRISPRi Flow-FISH CRISPR screen in K562 for COPZ1 (ENCSR029BRD)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000000D
CRISPRi Flow-FISH CRISPR screen in K562 for TRIR (ENCSR101JKC)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000000E
CRISPRi Flow-FISH CRISPR screen in K562 for KLF1 (ENCSR114BIZ)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000010
CRISPRi Flow-FISH CRISPR screen in K562 for ITGA5 (ENCSR116BPW)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000011
CRISPRi Flow-FISH CRISPR screen in K562 for OTUD5 (ENCSR138CXY)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000012
CRISPRi Flow-FISH CRISPR screen in K562 for BCAT2 (ENCSR154GRV)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000014
CRISPRi Flow-FISH CRISPR screen in K562 for LYL1 (ENCSR176XPW)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000015
CRISPRi Flow-FISH CRISPR screen in K562 for DHPS (ENCSR245NIU)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000017
CRISPRi Flow-FISH CRISPR screen in K562 for PQBP1 (ENCSR245ZZP)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000018
CRISPRi Flow-FISH CRISPR screen in K562 for CNBP (ENCSR306ZVG)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000001A
CRISPRi Flow-FISH CRISPR screen in K562 for RAD23A (ENCSR324QDY)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000001B
CRISPRi Flow-FISH CRISPR screen in K562 for DNASE2 (ENCSR336WSZ)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000001C
CRISPRi Flow-FISH CRISPR screen in K562 for EBP (ENCSR376SMC)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000001D
CRISPRi Flow-FISH CRISPR screen in K562 for RPN1 (ENCSR380BWA)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000001E
CRISPRi Flow-FISH CRISPR screen in K562 for BAX (ENCSR473FYG)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000020
CRISPRi Flow-FISH CRISPR screen in K562 for WDR83OS (ENCSR532VIG)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000022
CRISPRi Flow-FISH CRISPR screen in K562 for HDAC6 (ENCSR541HXR)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000023
CRISPRi Flow-FISH CRISPR screen in K562 for NFE2 (ENCSR617XYY)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000024
CRISPRi Flow-FISH CRISPR screen in K562 for PPP1R15A (ENCSR661PUY)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000025
CRISPRi Flow-FISH CRISPR screen in K562 for PLP2 (ENCSR752CCF)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000026
CRISPRi Flow-FISH CRISPR screen in K562 for SEC61A1 (ENCSR760TSA)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000027
CRISPRi Flow-FISH CRISPR screen in K562 for CALR (ENCSR858PBD)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000029
CRISPRi Flow-FISH CRISPR screen in K562 for GATA1 (ENCSR876DIL)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000002A
CRISPRi Flow-FISH CRISPR screen in K562 for RAB7A (ENCSR884HBT)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000002B
CRISPRi Flow-FISH CRISPR screen in K562 for NUCB1 (ENCSR884XXE)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000002C
CRISPRi Flow-FISH CRISPR screen in K562 for FUT1 (ENCSR898QMI)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000002D
CRISPRi Flow-FISH CRISPR screen in K562 for RNASEH2A (ENCSR905FEH)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000002E
CRISPRi Flow-FISH CRISPR screen in K562 for JUNB (ENCSR905MSH)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR000000002F
CRISPRi Flow-FISH CRISPR screen in K562 for HNRNPA1 (ENCSR922PHL)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000030
CRISPRi Flow-FISH CRISPR screen in K562 for FTL (ENCSR954IYH)
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000031
CRISPRi proliferation CRISPR screen in DU 145
＋
Homo sapiens DU 145 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: DU 145
DCPEXPR0000000032
CRISPRi proliferation CRISPR screen in MCF-7
＋
Homo sapiens MCF-7 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: MCF-7
DCPEXPR0000000033
CRISPRi proliferation CRISPR screen in SW620
＋
Homo sapiens SW620 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: SW620
DCPEXPR0000000034
CRISPRi proliferation CRISPR screen in HepG2
＋
Homo sapiens HepG2 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: HepG2
DCPEXPR0000000035
CRISPRi proliferation CRISPR screen in MDA-MB-231
＋
Homo sapiens MDA-MB-231 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: MDA-MB-231
DCPEXPR0000000036
CRISPRi proliferation CRISPR screen in PC-3
＋
Homo sapiens PC-3 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: PC-3
DCPEXPR0000000037
CRISPRi proliferation CRISPR screen in K562
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: K562
DCPEXPR0000000038
CRISPRi proliferation CRISPR screen in NCI-H460
＋
Homo sapiens NCI-H460 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: NCI-H460
DCPEXPR0000000039
CRISPRi proliferation CRISPR screen in HCT116
＋
Homo sapiens HCT116 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: HCT116
DCPEXPR000000003A
CRISPRi proliferation CRISPR screen in A549
＋
Homo sapiens A549 genetically modified (insertion) using transduction, using CRISPRi (pgRNA) for multiple loci
Cell Lines: A549
DCPEXPR000000003B
CRISPRi proliferation CRISPR screen in K562
＋
K562 cell line genetically modified (CRISPRi) using CRISPR, genetically modified (insertion) using transduction
Cell Lines: K562
DCPEXPR000000003C
CRISPRi proliferation CRISPR screen in HCT116
＋
HCT116 cell line genetically modified (CRISPRi) using CRISPR, genetically modified (insertion) using transduction
Cell Lines: HCT116
DCPEXPR000000003D
CRISPRi Flow-FISH CRISPR screen in K562
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chr8:126736096-128735246
Cell Lines: K562
DCPEXPR000000003E
CRISPRi Flow-FISH CRISPR screen in K562
＋
Homo sapiens K562 genetically modified (insertion) using transduction, using CRISPRi (sgRNA) for chr8:126736096-128735246
Cell Lines: K562
DCPEXPR000000003F